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Diagnosis & Tests

Medical Tests for Erectile Dysfunction

Understanding the various medical tests used to diagnose erectile dysfunction and identify underlying causes for effective treatment planning.

Why Medical Tests Are Important

Medical tests help doctors identify the underlying causes of erectile dysfunction, which is crucial for developing an effective treatment plan. Since ED can be caused by physical, psychological, or mixed factors, comprehensive testing ensures the right approach.

Key Goal: Determine whether ED is caused by physical problems (vascular, neurological, hormonal), psychological factors, or a combination of both.

Blood Tests

Hormone Tests

Testosterone Levels

  • Total testosterone: Overall hormone level
  • Free testosterone: Active, available hormone
  • Bioavailable testosterone: Usable by body
  • Normal range: 300-1000 ng/dL (total)
  • Best time: Morning (8-10 AM)

Other Hormones

  • LH (Luteinizing Hormone): Stimulates testosterone
  • FSH (Follicle Stimulating Hormone): Sperm production
  • Prolactin: Can suppress testosterone if high
  • TSH (Thyroid): Affects metabolism and libido
  • SHBG: Protein that binds testosterone

Metabolic Tests

Diabetes Screening

  • • Fasting glucose
  • • HbA1c (3-month average)
  • • Glucose tolerance test
  • • Insulin levels

Cardiovascular Risk

  • • Total cholesterol
  • • LDL ("bad") cholesterol
  • • HDL ("good") cholesterol
  • • Triglycerides

General Health

  • • Complete blood count
  • • Kidney function
  • • Liver function
  • • Vitamin D levels

Physical Examination

General Physical Exam

  • Vital signs: Blood pressure, heart rate, weight
  • Cardiovascular: Heart sounds, pulse strength
  • Neurological: Reflexes, sensation testing
  • Endocrine: Signs of hormone imbalance
  • Vascular: Peripheral pulse examination

Genital Examination

  • Penis: Size, shape, any abnormalities
  • Testicles: Size, consistency, masses
  • Prostate: Digital rectal exam (if indicated)
  • Peyronie's disease: Plaque or curvature
  • Sensation: Nerve function testing

Specialized Diagnostic Tests

Vascular Tests

Penile Doppler Ultrasound

Measures blood flow to and from the penis using sound waves.

  • • Injection of vasodilator medication
  • • Measurement of arterial blood flow
  • • Assessment of venous leakage
  • • Takes 30-60 minutes

Intracavernosal Injection Test

Direct injection into penis to test erectile response.

  • • Uses prostaglandin E1 or similar
  • • Evaluates erectile response
  • • Tests blood vessel function
  • • May cause temporary erection

Neurological Tests

Penile Biothesiometry

Tests nerve sensitivity in the penis using vibration.

  • • Measures vibration sensation
  • • Detects nerve damage
  • • Non-invasive procedure
  • • Takes 10-15 minutes

Bulbocavernosus Reflex

Tests nerve pathways involved in erection.

  • • Stimulation of glans penis
  • • Measures reflex response
  • • Evaluates spinal cord function
  • • Quick office procedure

Sleep Studies

Nocturnal Penile Tumescence (NPT)

Monitors erections during sleep to distinguish physical from psychological causes.

  • • Overnight monitoring device
  • • Measures frequency and rigidity
  • • Normal: 3-5 erections per night
  • • Can be done at home

RigiScan Testing

Advanced monitoring of nocturnal erections with detailed measurements.

  • • Measures rigidity and tumescence
  • • Multiple nights of monitoring
  • • Computer analysis of data
  • • Gold standard for NPT testing

Understanding Test Results

Normal Results Suggest

  • Normal NPT: Physical function intact, likely psychological cause
  • Normal blood flow: Vascular system functioning properly
  • Normal hormones: Endocrine system not the cause
  • Normal nerves: Neurological function preserved

Abnormal Results May Indicate

  • Poor blood flow: Vascular ED requiring specific treatment
  • Low testosterone: Hormone replacement may help
  • Nerve damage: Neurogenic ED, often from diabetes
  • Venous leak: Blood doesn't stay trapped in penis

When Are These Tests Needed?

Always Recommended

  • • Medical history and physical exam
  • • Basic blood tests (testosterone, glucose)
  • • Blood pressure measurement
  • • Cholesterol screening

Sometimes Needed

  • • Doppler ultrasound
  • • Nocturnal erection testing
  • • Injection testing
  • • Specialized hormone tests

Rarely Needed

  • • Arteriography (X-ray of arteries)
  • • Cavernosometry (pressure testing)
  • • MRI of pelvis
  • • Nerve conduction studies

After Testing

Once testing is complete, your doctor will review the results and develop a personalized treatment plan based on the underlying causes identified. Most men can be successfully treated regardless of the test results.

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