ED Medications Guide
Learn about the most effective erectile dysfunction medications, including how they work, dosages, side effects, and which might be right for you.
How ED Medications Work
All FDA-approved ED medications are PDE5 inhibitors. They work by blocking an enzyme called phosphodiesterase type 5 (PDE5), which increases blood flow to the penis during sexual arousal.
Block PDE5
Inhibit the enzyme that restricts blood flow
Increase Blood Flow
Allow more blood to flow to the penis
Enable Erection
Support natural erection process
Compare ED Medications
Sildenafil
The first FDA-approved ED medication, known for its reliability and effectiveness.
25mg, 50mg, 100mg
4-6 hours
30-60 minutes
Take on empty stomach for best results
Tadalafil
Known as the 'weekend pill' due to its long-lasting effects.
2.5mg, 5mg, 10mg, 20mg
Up to 36 hours
30-60 minutes
Can be taken with or without food
Vardenafil
May work better for men with diabetes or other health conditions.
5mg, 10mg, 20mg
4-6 hours
25-60 minutes
Take on empty stomach for best results
Avanafil
The newest ED medication with the fastest onset time.
50mg, 100mg, 200mg
4-6 hours
15-30 minutes
Can be taken with or without food
Important Safety Information
Do NOT Take If You:
- • Take nitrates for chest pain
- • Take alpha-blockers for blood pressure
- • Have severe heart or liver problems
- • Have had a stroke or heart attack recently
- • Have low blood pressure
- • Are allergic to the medication
Common Side Effects:
- • Headache
- • Flushing
- • Upset stomach
- • Nasal congestion
- • Dizziness
- • Vision changes (rare)
Getting Started with ED Medication
ED medications require a prescription from a licensed healthcare provider. They'll evaluate your health, current medications, and determine the best treatment option for you.